Doe guided chitosan based nano-ophthalmic preparation against fungal keratitis

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Clinical utility of voriconazole eye drops in ophthalmic fungal keratitis

Fungal keratitis is one of the major causes of ophthalmic mycosis and is difficult to treat. The range of common antifungal agents available for fungal keratitis remains inadequate and is generally associated with poor clinical outcomes. Voriconazole is a new generation triazole antifungal agent. Only marketed in systemic formulation and, with broad-spectrum activity and high intraocular penetr...

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Fungal keratitis

CLINICAL QUESTION What is the most appropriate management of fungal keratitis? RESULTS Traditionally, topical Natamycin is the most commonly used medication for filamentous fungi while Amphotericin B is most commonly used for yeast. Voriconazole is rapidly becoming the drug of choice for all fungal keratitis because of its wide spectrum of coverage and increased penetration into the cornea. ...

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Fungal keratitis.

PURPOSE OF REVIEW Throughout the world, fungal keratitis is a leading cause of ocular morbidity. The purpose of this review is to discuss the recently published literature in relation to the epidemiology, etiology, diagnosis, and therapy of fungal keratitis. RECENT FINDINGS Globally, the incidence of keratomycoses and systemic mycoses is rising. Current therapies are often ineffective. Ongoin...

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Ophthalmic zoster: mucous plaque keratitis.

Data taken from 1221 patients attending the Zoster Clinic of Moorfields Eye Hospital over the past 15 years were used to characterise the clinical appearance and behaviour of zoster mucous plaque keratitis (MPK). The typical greyish branching plaques are usually accompanied by a limbitis, stromal keratitis, or decrease in corneal sensation and are commonly associated with cataract, raised intra...

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Fungal Keratitis Associated with Viral Keratitis

Microbial keratitis caused by more than one microorganism is rare. It may occur as a coinfection or as a secondary infection superimposed with an existent microorganism. [1] Both infectious and immune mechanisms are implicated in microbial keratitis. Herein, we report an unusual clinical case of viral and fungal mixed infection. Written informed consent was obtained from the patient. A 31‑year‑...

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ژورنال

عنوان ژورنال: Materials Today: Proceedings

سال: 2021

ISSN: 2214-7853

DOI: 10.1016/j.matpr.2020.09.823